13-(N,N-Di­methyl­amino)­micheliolide 0.08-hydrate

نویسندگان

  • Shobanbabu Bommagani
  • Narsimha Reddy Penthala
  • Venumadhav Janganati
  • Sean Parkin
  • Peter A. Crooks
چکیده

The title compound, C17H27NO3·0.08H2O {sytematic name: (3R,3aS,9R,9aS,9bS)-3-[(di-methyl-amino)-meth-yl]-9-hy-droxy-6,9-dimethyl-3,3a,4,5,7,8,9,9a-octa-hydro-azuleno[4,5-b]furan-2(9bH)-one 0.08-hydrate}, exhibits intra-molecular O-H⋯O hydrogen bonding to form a ring of graph-set motif S(6). As well as this intra-molecular hydrogen bond with the lactone-ring O atom, the hy-droxy H atom forms an O-H⋯O hydrogen bond to the low-occupancy partial water mol-ecule [occupancy = 0.078 (2)]. The water mol-ecule is correlated with disorder of the N(CH3)2 group [major-minor occupancy factors are 0.922 (2):0.078 (2)]. The dihedral angle between the mean planes of the trans-fused seven-membered ring and the lactone ring is 4.42 (9)°.

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عنوان ژورنال:

دوره 69  شماره 

صفحات  -

تاریخ انتشار 2013